Detalhe da pesquisa
1.
Discovery of Human Signaling Systems: Pairing Peptides to G Protein-Coupled Receptors.
Cell
; 179(4): 895-908.e21, 2019 10 31.
Artigo
em Inglês
| MEDLINE | ID: mdl-31675498
2.
Identification of a ß-arrestin-biased negative allosteric modulator for the ß2-adrenergic receptor.
Proc Natl Acad Sci U S A
; 120(31): e2302668120, 2023 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-37490535
3.
In silico identification of a ß2-adrenoceptor allosteric site that selectively augments canonical ß2AR-Gs signaling and function.
Proc Natl Acad Sci U S A
; 119(49): e2214024119, 2022 12 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-36449547
4.
The biased M3 mAChR ligand PD 102807 mediates qualitatively distinct signaling to regulate airway smooth muscle phenotype.
J Biol Chem
; 299(10): 105209, 2023 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-37660916
5.
Mendelian Randomization Analysis Reveals a Complex Genetic Interplay among Atopic Dermatitis, Asthma, and Gastroesophageal Reflux Disease.
Am J Respir Crit Care Med
; 207(2): 130-137, 2023 01 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-36214830
6.
Prorelaxant E-type Prostanoid Receptors Functionally Partition to Different Procontractile Receptors in Airway Smooth Muscle.
Am J Respir Cell Mol Biol
; 69(5): 584-591, 2023 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-37523713
7.
Crosstalk between diacylglycerol kinase and protein kinase A in the regulation of airway smooth muscle cell proliferation.
Respir Res
; 24(1): 155, 2023 Jun 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-37301818
8.
The odorant receptor OR2W3 on airway smooth muscle evokes bronchodilation via a cooperative chemosensory tradeoff between TMEM16A and CFTR.
Proc Natl Acad Sci U S A
; 117(45): 28485-28495, 2020 11 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-33097666
9.
PD 102807 Induces M3 mAChR-Dependent GRK-/Arrestin-Biased Signaling in Airway Smooth Muscle Cells.
Am J Respir Cell Mol Biol
; 67(5): 550-561, 2022 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-35944139
10.
Autocrine regulation of airway smooth muscle contraction by diacylglycerol kinase.
J Cell Physiol
; 237(1): 603-616, 2022 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-34278583
11.
Cooperativity between ß-agonists and c-Abl inhibitors in regulating airway smooth muscle relaxation.
FASEB J
; 35(7): e21674, 2021 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-34115899
12.
Regulation of Airway Smooth Muscle Cell Proliferation by Diacylglycerol Kinase: Relevance to Airway Remodeling in Asthma.
Int J Mol Sci
; 23(19)2022 Oct 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-36233170
13.
Diacylglycerol Kinase Inhibition Reduces Airway Contraction by Negative Feedback Regulation of Gq-Signaling.
Am J Respir Cell Mol Biol
; 65(6): 658-671, 2021 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-34293268
14.
A tripartite cooperative mechanism confers resistance of the protein kinase A catalytic subunit to dephosphorylation.
J Biol Chem
; 295(10): 3316-3329, 2020 03 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-31964716
15.
OGR1-dependent regulation of the allergen-induced asthma phenotype.
Am J Physiol Lung Cell Mol Physiol
; 321(6): L1044-L1054, 2021 12 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-34668419
16.
Increased expression of desmin and vimentin reduces bladder smooth muscle contractility via JNK2.
FASEB J
; 34(2): 2126-2146, 2020 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-31909533
17.
Allosteric ligands for the pharmacologically dark receptors GPR68 and GPR65.
Nature
; 527(7579): 477-83, 2015 Nov 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-26550826
18.
Can GPCRs Be Targeted to Control Inflammation in Asthma?
Adv Exp Med Biol
; 1304: 1-20, 2021.
Artigo
em Inglês
| MEDLINE | ID: mdl-34019260
19.
NF-κB and GATA-Binding Factor 6 Repress Transcription of Caveolins in Bladder Smooth Muscle Hypertrophy.
Am J Pathol
; 189(4): 847-867, 2019 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-30707892
20.
Specificity of NHERF1 regulation of GPCR signaling and function in human airway smooth muscle.
FASEB J
; 33(8): 9008-9016, 2019 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-31042404